Discovering new bait for the immune system may lead to additional treatments for melanoma

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LEXINGTON, MA, USA I September 11, 2020 I Partner Therapeutics, Inc. (PTx), a commercial biotech company, announces the resumption of enrollment in the National Cancer Institute (NCI) sponsored Study EA61411 being conducted by ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and led by Study Chair F. Stephen Hodi, MD, Director of the Center for Immuno-Oncology at Dana-Farber Cancer Institute and Study Co-Chair Ahmad Tarhini, MD, PhD. , Professor of Oncologic Sciences and Director of Cutaneous and Clinical Translational Research at H. Lee Moffitt Proven Peptides Review 2019 Cancer Center and Research Institute. EA6141 (NCT02339571) is a randomized controlled study of Leukine (sargramostim, yeast derived rhu-GM-CSF) in combination with ipilimumab and nivolumab for the front line treatment of melanoma. The restart was based on results of ECOG-ACRIN's planned interim efficacy and safety analysis of survival data from the first 250 patients enrolled in the study. In September 2019 the U. S. Food and Drug Administration (FDA) granted orphan drug status to Leukine, for the potential treatment of stage IIb-IV melanoma.

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